General Information

  • ID:  hor001090
  • Uniprot ID:  NA
  • Protein name:  FMRFamide-related peptide
  • Gene name:  NA
  • Organism:  Locusta migratoria
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GQERNFLRF
  • Length:  9
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T9 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Have an inhibitory effect, decreasing the amplitude of neurally evoked spermathecal contractions.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001090_AF2.pdbhor001090_ESM.pdb

Physical Information

Mass: 130917 Formula: C52H79N17O14
Absent amino acids: ACDHIKMPSTVWY Common amino acids: FR
pI: 10.4 Basic residues: 2
Polar residues: 2 Hydrophobic residues: 3
Hydrophobicity: -116.67 Boman Index: -3701
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 43.33
Instability Index: 4870 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  11897379
  • Title:  Evidence for the Association of FMRFamide-related Peptides With the Spermatheca of Locusta Migratoria